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高野 仁司

循环内科 ・心绞痛名医


高野 仁司
タカノ ヒトシ
循环器内科 ・心绞痛(心脏导管术) 的名医

 
专业领域
循环器内科、内科全般

简历
2012年4月 - 现在   日本医科大学 医学部 循环器内科  准教授
2010年4月 - 2012年3月   日本医科大学 循环器内科  讲师
2001年4月 - 2010年3月   日本医科大学 第一内科  助手
2000年1月 - 2001年3月   国立东静医院 循环器内科  医师
1999年12月 - 1999年12月   日本医科大学 第一内科  助手
1996年11月 - 1999年11月   路易斯维尔大学 心脏病部门  研究员
1996年1月 - 1996年10月   日本医科大学 第一内科  研究生
1995年4月 - 1995年12月   日本医科大学多摩永山医院 内科  助手
1993年4月 - 1995年3月   北村山公立病院 内科  医师
1991年6月 - 1993年3月   日本医科大学 医学部 循环器内科 第一内科  研修医

委员历
2018年10月 – 现在   日本心血管介入治疗学会  专业医制度委员会委员
2018年8月 - 现在   日本循环器学会   新专业医制度讨论构筑部会委员
2018年7月 - 现在   日本循环器学会  专业医制度委员会干事
2016年4月 - 现在   日本循环器学会  社员
2013年8月 - 现在   日本冠疾患学会  保险委员会副委员长
2011年9月 - 现在   日本心血管内视镜学会  理事
2009年11月 - 现在   日本冠疾患学会  评议员
• 2009年4月 - 现在   日本心血管介入治疗学会  评议员

所属学会
日本心血管介入治疗学会
日本心血管内视镜学会
日本冠疾患学会
日本集中治疗医学会
日本心脏病学会
日本循环器学会
日本内科学会
日本高血压学会
美国心脏协会同事(FAHA)
美国心脏病协会同事(fACC)

得奖
2016年9月   日本冠疾患学会杂志 Best Reviewer奖
2006年11月   2006 Scientific Sessions of the American Heart Association Scientific Award Clinical Session
2006年10月   TCT2006 Datascope Scholarship Award
1998年2月   American Heart Association Young Investigator Award in the meeting of Vascular and Myocardial Aspects of Ischemic Heart Disease
1998年7月   American Heart Association Kentucky Affiliate Fellowship Award

论文
Effect of Empagliflozin Versus Placebo on Cardiac Sympathetic Activity in Acute Myocardial Infarction Patients with Type 2 Diabetes Mellitus: Rationale.
Kubota Y, Yamamoto T, Tara S, Tokita Y, Yodogawa K, Iwasaki Y, Takano H, Tsukada Y, Asai K, Miyamoto M, Miyauchi Y, Kodani E, Sato N, Tanabe J, Shimizu W
Diabetes therapy : research, treatment and education of diabetes and related disorders 9(5) 2107-2116 2018年10月

Haemodynamic deterioration due to intra-aortic balloon counterpulsation in takotsubo cardiomyopathy.
Sangen H, Imori Y, Tara S, Yamamoto T, Takano H, Shimizu W
European heart journal 39(22) 2118 2018年6月

IgG4-related periarteritis in the coronary artery and subclinical pericarditis assessed the presence and monitoring of therapy response by PET and CT scan.
Matsuda J, Takano H, Shimizu W
BMJ case reports 2018 2018年6月

Cardiac MR Imaging of Hypertrophic Cardiomyopathy: Techniques, Findings, and Clinical Relevance.
Amano Y, Kitamura M, Takano H, Yanagisawa F, Tachi M, Suzuki Y, Kumita S, Takayama M
Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine 17(2) 120-131 2018年4月

Chronic phase improvements in electrocardiographic and echocardiographic manifestations of left ventricular hypertrophy after alcohol septal ablation for drug-refractory hypertrophic obstructive cardiomyopathy.
Matsuda J, Kitamura M, Takayama M, Imori Y, Shibuya J, Kubota Y, Sangen H, Nakamura S, Takano H, Asai K, Shimizu W
Heart and vessels 33(3) 246-254 2018年3月

Feasibility of combined risk stratification with coronary CT angiography and stress myocardial SPECT in patients with chronic coronary artery disease.
Kiriyama T, Fukushima Y, Hayashi H, Takano H, Kumita SI
Annals of nuclear medicine 32(1) 22-33 2018年1月

Diagnostic performance of hybrid cardiac SPECT/CT imaging for patients with takotsubo cardiomyopathy.
Sugihara Y, Fukushima Y, Kumita SI, Takano H, Shimizu W
European journal of hybrid imaging 2(1) 5 2018年

Time course of the antiplatelet effect after switching to clopidogrel from initial prasugrel therapy in patients with acute coronary syndrome.
Furuse E, Takano H, Yamamoto T, Kubota Y, Yoshizane T, Kitamura M, Miyachi H, Hosokawa Y, Shimizu W
Heart and vessels 32(12) 1432-1438 2017年12月

A novel application of the culotte stent technique to bail out a jailed common iliac artery.
Sangen H, Tara S, Tanaka T, Takano H, Tanaka K, Shimizu W
Journal of vascular surgery cases and innovative techniques 3(4) 236-239 2017年12月

Evaluation of myocardial glucose metabolism in hypertrophic cardiomyopathy using 18F-fluorodeoxyglucose positron emission tomography.
Aoyama R, Takano H, Kobayashi Y, Kitamura M, Asai K, Amano Y, Kumita SI, Shimizu W
PloS one 12(11) e0188479-e0188494 2017年11月

Usefulness of Non-Anteroseptal Region Left Ventricular Hypertrophy Using Cardiac Magnetic Resonance to Predict Repeat Alcohol Septal Ablation for Refractory Obstructive Hypertrophic Cardiomyopathy.
Kitamura M, Amano Y, Takayama M, Shibuya J, Matsuda J, Sangen H, Nakamura S, Takano H, Asai K, Kumita S, Shimizu W
The American journal of cardiology 120(1) 124-130 2017年7月

The impact of blood pressure variability on coronary plaque vulnerability in stable angina: an analysis using optical coherence tomography.
Aoyama R, Takano H, Suzuki K, Kubota Y, Inui K, Tokita Y, Shimizu W
Coronary artery disease 28(3) 225-231 2017年5月

Plaque Characteristics in Coronary Artery Disease Patients with Impaired Glucose Tolerance.
Suzuki K, Takano H, Kubota Y, Inui K, Nakamura S, Tokita Y, Kato K, Asai K, Shimizu W
PloS one 11(12) e0167645-e0167655 2016年12月

Geographical predisposition influences on the distribution and tissue characterisation of eccentric coronary plaques in non-branching coronary arteries: cross-sectional study of coronary plaques analysed by intravascular ultrasound.
Komiyama H, Takano H, Nakamura S, Takano M, Hata N, Yasushi M, Seino Y, Mizuno K, Shimizu W
Cardiovascular ultrasound 14(1) 47 2016年11月

Superiority of the extracellular volume fraction over the myocardial T1 value for the assessment of myocardial fibrosis in patients with non-ischemic cardiomyopathy.
Inui K, Tachi M, Saito T, Kubota Y, Murai K, Kato K, Takano H, Amano Y, Asai K, Shimizu W
Magnetic resonance imaging 34(8) 1141-1145 2016年10月

Characterization of real-world patients with low fractional flow reserve immediately after drug-eluting stents implantation.
Kimura Y, Tanaka N, Okura H, Yoshida K, Akabane M, Takayama T, Hirayama A, Tada T, Kimura T, Takano H, Mizuno K, Inami T, Yoshino H, Yamashina A
Cardiovascular intervention and therapeutics 31(1) 29-37 2016年1月

Autophagic vacuoles in cardiomyocytes of dilated cardiomyopathy with initially decompensated heart failure predict improved prognosis.
Saito T, Asai K, Sato S, Hayashi M, Adachi A, Sasaki Y, Takano H, Mizuno K, Shimizu W
Autophagy 12(3) 579-587 2016年

Impact of time-of-flight on qualitative and quantitative analyses of myocardial perfusion PET studies using (13)N-ammonia.
Tomiyama T, Ishihara K, Suda M, Kanaya K, Sakurai M, Takahashi N, Takano H, Nitta K, Hakozaki K, Kumita S
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology 22(5) 998-1007 2015年10月

Target lesion evaluation by multiple modalities in vivo: near-infrared spectroscopy (NIRS), virtual histology intravascular ultrasound, optical coherence tomography, and angioscopy.
Shibuya J, Nakamura S, Komiyama H, Kato K, Inami S, Takano H, Mizuno K, Shimizu W
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 11(6) e1 2015年10月

Proton pump inhibitors are associated with lower gastrointestinal tract bleeding in low-dose aspirin users with ischaemic heart disease.
Miyake K, Akimoto T, Hanada Y, Nagoya H, Kodaka Y, Ueki N, Kusunoki M, Kawagoe T, Futagami S, Takahashi Y, Takano H, Sakamoto C
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 47(9) 757-762 2015年9月

Clinical Characteristics and Outcome of Alcohol Septal Ablation With Confirmation by Nitroglycerin Test for Drug-Refractory Hypertrophic Obstructive Cardiomyopathy With Labile Left Ventricular Outflow Obstruction.
Kitamura M, Takayama M, Matsuda J, Kubota Y, Nakamura S, Takano H, Asai K, Shimizu W
The American journal of cardiology 116(6) 945-951 2015年9月

Successful early diagnosis and treatment in a case of Toxocara canis-induced eosinophilic myocarditis with eosinophil-rich pericardial effusion.
Sangen H, Tanabe J, Takano H, Shimizu W
BMJ case reports 2015 2015年9月

Impact of Brain Natriuretic Peptide, Calcium Channel Blockers, and Body Mass Index on Recovery Time from Left Ventricular Systolic Dysfunction in Patients With Takotsubo Cardiomyopathy.
Shiomura R, Nakamura S, Takano H, Kato K, Inui K, Kubota Y, Komiyama H, Murai K, Asai K, Shimizu W
The American journal of cardiology 116(4) 515-519 2015年8月

Patients with reduced heart rate response to adenosine infusion have low myocardial flow reserve in (13)N-ammonia PET studies.
Tomiyama T, Kumita S, Ishihara K, Suda M, Sakurai M, Hakozaki K, Hashimoto H, Takahashi N, Takano H, Kobayashi Y, Kiriyama T, Fukushima Y, Shimizu W
The international journal of cardiovascular imaging 31(5) 1089-1095 2015年6月

Drug-resistant vasospastic angina pectoris with plaque erosion in the focal spastic lesion confirmed with coronary angioscopy.
Koen M, Nakamura S, Takano H, Shimizu W
BMJ case reports 2015 2015年6月

Ultrastructural features of cardiomyocytes in dilated cardiomyopathy with initially decompensated heart failure as a predictor of prognosis.
Saito T, Asai K, Sato S, Takano H, Mizuno K, Shimizu W
European heart journal 36(12) 724-732 2015年3月

Impact of sleep-disordered breathing and efficacy of positive airway pressure on mortality in patients with chronic heart failure and sleep-disordered breathing: a meta-analysis.
Nakamura S, Asai K, Kubota Y, Murai K, Takano H, Tsukada YT, Shimizu W
Clinical research in cardiology : official journal of the German Cardiac Society 104(3) 208-216 2015年3月

Relationship between cholesterol crystals and culprit lesion characteristics in patients with stable coronary artery disease: an optical coherence tomography study.
Nakamura S, Inami S, Murai K, Takano M, Takano H, Asai K, Yasutake M, Shimizu W, Mizuno K
Clinical research in cardiology : official journal of the German Cardiac Society 103(12) 1015-1021 2014年12月

Prognostic values of highly sensitive cardiac troponin T and B-type natriuretic peptide for clinical features in hypertrophic obstructive cardiomyopathy: a cross-sectional study.
Nakamura S, Takano H, Matsuda J, Chinen D, Kitamura M, Murai K, Asai K, Yasutake M, Takayama M, Shimizu W
BMJ open 4(9) e005968 2014年9月

Impact of the efficacy of thrombolytic therapy on the mortality of patients with acute submassive pulmonary embolism: a meta-analysis.
Nakamura S, Takano H, Kubota Y, Asai K, Shimizu W
Journal of thrombosis and haemostasis : JTH 12(7) 1086-1095 2014年7月

Alcohol septal ablation with septal myocardial isolation using the double-balloon method for refractory hypertrophic obstructive cardiomyopathy.
Kitamura M, Kubota Y, Takano H, Takayama M
European heart journal 35(4) 241 2014年1月

Acute myocarditis associated with coxsackievirus B4 mimicking influenza myocarditis: electron microscopy detection of causal virus of myocarditis.
Ikeda T, Saito T, Takagi G, Sato S, Takano H, Hosokawa Y, Hayashi M, Asai K, Yasutake M, Mizuno K
Circulation 128(25) 2811-2812 2013年12月

Proof of myocardial autophagy by combining antigen retrieval and the avidin-biotin peroxidase complex method.
Saito T, Asai K, Sato S, Takano H, Adach A, Sasaki Y, Namimatsu S, Mizuno K
International journal of cardiology 168(5) 4843-4844 2013年10月

Myocardial alterations and clinical implications associated with recovery of cardiac function in dilated cardiomyopathy with obesity.
Saito T, Asai K, Sato S, Takagi G, Takano H, Takahashi H, Yasutake M, Mizuno K
International journal of cardiology 168(1) 144-150 2013年9月

Comparison of perfusion-metabolism mismatch in 99mTc-MIBI and 123I-BMIPP scintigraphy with cardiac magnetic resonance in patients with dilated cardiomyopathy.
Yoshida A, Takano H, Asai K, Yasutake M, Amano Y, Kumita S, Shimizu W, Mizuno K
Journal of cardiac failure 19(7) 445-453 2013年7月

Usefulness of rosuvastatin to prevent periprocedural myocardial injury in patients undergoing elective coronary intervention.
Takano H, Ohba T, Yamamoto E, Miyachi H, Inui K, Kawanaka H, Kamiya M, Kikuchi A, Takahashi Y, Tanabe J, Inami S, Takagi G, Asai K, Yasutake M, Ibuki C, Tanaka K, Kusama Y, Seino Y, Munakata K, Mizuno K, PRIMITIVE Study Investigators.
The American journal of cardiology 111(12) 1688-1693 2013年6月

Inhaled nitric oxide therapy for secondary pulmonary hypertension with hypertrophic obstructive cardiomyopathy and severe kyphoscoliosis.
Hosokawa Y, Yamamoto T, Yabuno Y, Hara K, Aokage T, Nakazato K, Suzuki H, Suzuki M, Ueno A, Munakata R, Tokita Y, Yamamoto E, Akutsu K, Takano H, Sato N, Takayama M, Tanaka K, Mizuno K
International journal of cardiology 158(1) e20-1 2012年6月

Disruption of atherosclerotic neointima seven years after bare metal stent deployment.
Inami S, Takano M, Kato K, Yoshida A, Nakamura S, Murai K, Tokita Y, Takagi G, Takano H, Asai K, Yasutake M, Mizuno K
International heart journal 53(4) 261-262 2012年

Controlled-release basic fibroblast growth factor for peripheral artery disease: comparison with autologous bone marrow-derived stem cell transfer.
Takagi G, Miyamoto M, Tara S, Takagi I, Takano H, Yasutake M, Tabata Y, Mizuno K
Tissue engineering. Part A 17(21-22) 2787-2794 2011年11月

Novel approach to ischemic skin ulcer in systemic lupus erythematosus: therapeutic angiogenesis by controlled-release basic fibroblast growth factor.
Tara S, Takagi G, Miyamoto M, Kirinoki-Ichikawa S, Yamamoto T, Takano H, Takagi I, Yasutake M, Tabata Y, Mizuno K
Geriatrics & gerontology international 11(4) 527-530 2011年10月

Coronary angioscopy: current topics and future direction.
Mizuno K, Wang Z, Inami S, Takano M, Yasutake M, Asai K, Takano H
Cardiovascular intervention and therapeutics 26(2) 89-97 2011年5月

Elevated peripheral blood mononuclear cell count is an independent predictor of left ventricular remodeling in patients with acute myocardial infarction.
Aoki S, Nakagomi A, Asai K, Takano H, Yasutake M, Seino Y, Mizuno K
Journal of cardiology 57(2) 202-207 2011年3月

SNPs on chromosome 5p15.3 associated with myocardial infarction in Japanese population.
Aoki A, Ozaki K, Sato H, Takahashi A, Kubo M, Sakata Y, Onouchi Y, Kawaguchi T, Lin TH, Takano H, Yasutake M, Hsu PC, Ikegawa S, Kamatani N, Tsunoda T, Juo SH, Hori M, Komuro I, Mizuno K, Nakamura Y, Tanaka T
Journal of human genetics 56(1) 47-51 2011年1月

Prediction of limb salvage after therapeutic angiogenesis by autologous bone marrow cell implantation in patients with critical limb ischemia.
Tara S, Miyamoto M, Takagi G, Fukushima Y, Kirinoki-Ichikawa S, Takano H, Takagi I, Mizuno H, Yasutake M, Kumita S, Mizuno K
Annals of vascular diseases 4(1) 24-31 2011年

Discordance between the morphological and physiological information of 64-slice MSCT coronary angiography and myocardial perfusion imaging in patients with intermediate to high probability of coronary artery disease.
Kiriyama T, Toba M, Fukushima Y, Hayashi H, Takano H, Mizuno K, Kumita S
Circulation journal : official journal of the Japanese Circulation Society 75(7) 1670-1677 2011年

Secondary preventive effects of a calcium antagonist for ischemic heart attack: randomized parallel comparison with β-blockers.
Nakagomi A, Kodani E, Takano H, Uchida T, Sato N, Ibuki C, Kusama Y, Seino Y, Munakata K, Mizuno K, Takano T
Circulation journal : official journal of the Japanese Circulation Society 75(7) 1696-1705 2011年

Optical coherence tomography after new scoring balloon angioplasty for in-stent restenosis and de novo coronary lesions.
Takano M, Yamamoto M, Murakami D, Takano H, Asai K, Yasutake M, Seino Y, Mizuno K
International journal of cardiology 141(3) e51-3 2010年6月

Therapeutic angiogenesis by controlled-release fibroblast growth factor in a patient with Churg-Strauss syndrome complicated by an intractable ischemic leg ulcer.
Kawanaka H, Takagi G, Miyamoto M, Tara S, Takagi I, Takano H, Yasutake M, Tabata Y, Mizuno K
The American journal of the medical sciences 338(4) 341-342 2009年10月

Impact of percutaneous transluminal septal myocardial ablation on refractory paroxysmal atrial fibrillation in patients with hypertrophic obstructive cardiomyopathy.
Hosokawa Y, Takano H, Ohno T, Takayama M, Takano T.
Angiology. 2008 Jun-Jul;59(3):329-34. 59(3) 329-334 2008年

Direct comparison between pharmacological stress with adenosine triphosphate disodium and exercise stress myocardial perfusion imagings.
Ohba T, Takano H, Kunimi T, Fujita N, Kodani E, Mizuno K.
J Cardiol. 52(1) 30-38 2008年

Management of coronary artery disease in patients undergoing elective abdominal aortic aneurysm open repair
Hosokawa, Y. Takano, H. Aoki, A. Inami, T. Ogano, M. Kobayashi, N. Tanabe, J. Yokoyama, H. Kato, T. Takagi, H. Umemoto, T. Takayama, M. Mizuno, K
Clin Cardiol 31(12) 580-585 2008年

Clinical outcome and quality of life of octogenarian patients following percutaneous coronary intervention or surgical coronary revascularization.
Kamiya M, Takayama M, Takano H, Murai K, Hinokiyama K, Ochi M, Takano T.
Circ J. 71(6) 847-854 2007年

Coronary perforation during percutaneous coronary intervention.
Shirakabe A, Takano H, Nakamura S, Kikuchi A, Sasaki A, Yamamoto E, Kawashima S, Takagi G, Fujita N, Aoki S, Asai K, Yoshikawa M, Kato K, Yamamoto T, Takayama M, Takano T.
Int Heart J. 2007 Jan;48(1):1-9. 48(1) 1-9 2007年

Late multiple stent fractures following deployment of sirolimus-eluting stents for diffuse right coronary artery stenosis.
Aoki A, Tanabe J, Inami T, Ogano M, Kobayashi N, Hosokawa Y, Yokoyama H, Takano H, Mizuno K.
Int Heart J. 48(6) 767-772 2007年

コレステロール結晶塞栓症(CCE) ステロイド療法とLDLアフェレーシス併用の効果
岡崎怜子, 菊池有史, 平山悦之, 丸山光紀, 高木元, 高野仁司, 高山守正, 小林義典, 高野照夫, 高田大輔, 金子朋広, 飯野靖彦, 片山泰朗, 三石剛, 川名誠司, 葉山修陽
日本医科大学医学会雑誌 2 115-120 2006年

Percutaneous coronary intervention under the rigid restriction of contrast media dose in patients with chronic renal insufficiency.
Yamamoto E, Takano H, Takayama M.
J Invasive Cardiol. 18(6) E169-172 2006年

Prophylactic hemodialysis does not prevent contrast-induced nephropathy after cardiac catheterization in patients with chronic renal insufficiency.
Kawashima S, Takano H, Iino Y, Takayama M, Takano T.
Circ J. 70(5) 553-558 2006年

Successful colectomy for the treatment of repetitive bleeding from colonic angiodysplasia in a patient with Heyde syndrome.
Ogano M, Iwasaki YK, Takano H, Takayama M, Takano T, Fukuda Y
Internal medicine (Tokyo, Japan) 45(6) 355-358 2006年

Sudden death in a case of cardiac amyloidosis immediately after pacemaker implantation for complete atrioventricular block.
Ogano M, Takano H, Fukuma N, Takayama M, Takano T, Miyagi Y, Ochi M, Shimizu K, Kitamura H
Journal of Nippon Medical School = Nippon Ika Daigaku zasshi 72(5) 285-289 2005年10月

Pharmacological preconditioning with bradykinin affords myocardial protection through NO-dependent mechanisms.
Yoshida H, Kusama Y, Kodani E, Yasutake M, Takano H, Atarashi H, Kishida H, Takano T
International heart journal 46(5) 877-887 2005年9月

多剤服用でコントロール不十分な高血圧症例に対する高用量バルサルタンの臨床効果
高野 仁司
セラピューティック・リサーチ 26(10) 2037-2042 2005年

Hypercholesterolemia abrogates late preconditioning via a tetrahydrobiopterin-dependent mechanism in conscious rabbits
Tang XL, Takano H, Xuan YT, Sato H, Kodani E, Dawn B, Zhu Y, Shirk G, Wu WJ, Bolli R.
Circulation 112(14) 2149-2156 2005年

Cardioprotection during the final stage of the late phase of ischemic preconditioning is mediated by neuronal NO synthase in concert with cyclooxygenase-2.
Wang Y, Kodani E, Wang J, Zhang SX, Takano H, Tang XL, Bolli R.
Circ Res 95(1) 84-91 2004年

Therapeutic angiogenesis by autologous bone marrow cell implantation for refractory chronic peripheral arterial disease using assessment of neovascularization by 99mTc-tetrofosmin (TF) perfusion scintigraphy.
Miyamoto M, Yasutake M, Takano H, Takagi H, Takagi G, Mizuno H, Kumita S, Takano T
Cell transplantation 13(4) 429-437 2004年

難治性疾患への再生医療:重症難治性心血管疾患に対する自己骨髄細胞を利用した新しい血管再生治療,
宮本正章, 安武正弘, 高野仁司, 高木 元, 高木啓倫, 水野博司, 汲田伸一郎, 落 雅美, 坂本篤裕, 高野照夫.
麻酔 52 Suppl S67-75 2003年12月

孤立性中流部閉塞性肥大型心筋症に対する経皮的心筋中隔焼灼術
細川雄亮, 高野仁司*, Jihad Z, 中込明裕, 高山守正
日本心血管インターベンション学会誌 18 549-556 2003年

Protein tyrosine kinase signaling is necessary for NO donor-induced late preconditioning against myocardial stunning.
Tang XL, Kodani E, Takano H, Hill M, Shinmura K, Vondriska TM, Ping P, Bolli R.
Am J Physiol Heart Circ Physiol 284(4) H1441-1448 2003年

Delta-opioid receptor-induced late preconditioning is mediated by cyclooxygenase-2 in conscious rabbits.
Kodani E, Xuan YT, Shinmura K, Takano H, Tang XL, Bolli R
American journal of physiology. Heart and circulatory physiology 283(5) H1943-57 2002年11月

Role of Src protein tyrosine kinases in late preconditioning against myocardial infarction.
Dawn B, Takano H, Tang XL, Kodani E, Banerjee S, Rezazadeh A, Qiu Y, Bolli R.
Am J Physiol Heart Circ Physiol. 283(2) H549-556 2002年

Role of cyclic guanosine monophosphate in late preconditioning in conscious rabbits.
Kodani E, Xuan YT, Takano H, Shinmura K, Tang XL, Bolli R.
Circulation 105(25) 3046-3052 2002年

Oxidant species trigger late preconditioning against myocardial stunning in conscious rabbits.
Tang XL, Takano H, Rizvi A, Turrens JF, Qiu Y, Wu WJ, Zhang Q, Bolli R.
Am J Physiol Heart Circ Physiol 282(1) H281-291 2002年

Effects of losartan on blood pressure and humoral factors in a patient who suffered from anaphylactoid reactions when treated with ACE inhibitors during LDL apheresis.
Kojima S, Shida M, Takano H, Inami S, Yodogawa K, Yokoyama H, Kuramochi M
Hypertension research : official journal of the Japanese Society of Hypertension 24(5) 595-598 2001年9月

Cyclooxygenase-2 does not mediate late preconditioning induced by activation of adenosine A1 or A3 receptors.
Kodani E, Shinmura K, Xuan YT, Takano H, Auchampach JA, Tang XL, Bolli R
American journal of physiology. Heart and circulatory physiology 281(2) H959-68 2001年8月

Renal macrostructure and cortical circulation in hypertension assessed by dynamic computed tomography.
Kojima S, Shida M, Tanaka K, Takano H, Yokoyama H, Kuramochi M
American journal of hypertension 14(6 Pt 1) 516-523 2001年6月

Acute changes in plasma levels of hepatocyte growth factor during low-density lipoprotein apheresis.
Kojima S, Shida M, Tanaka K, Takano H, Yokoyama H, Kuramochi M
Therapeutic apheresis : official journal of the International Society for Apheresis and the Japanese Society for Apheresis 5(1) 2-6 2001年2月

Nitroglycerin induces late preconditioning against myocardial infarction in conscious rabbits despite development of nitrate tolerance.
Hill M, Takano H, Tang XL, Kodani E, Shirk G, Bolli R.
Circulation 104(6) 694-699 2001年

A(1) or A(3) adenosine receptors induce late preconditioning against infarction in conscious rabbits by different mechanisms.
Takano H, Bolli R, Black RG Jr, Kodani E, Tang XL, Yang Z, Bhattacharya S, Auchampach JA.
Circ Res 88(5) 520-528 2001年

Late preconditioning enhances recovery of myocardial function after infarction in conscious rabbits.
Takano H, Tang XL, Kodani E, Bolli R.
Am J Physiol Heart Circ Physiol 279(5) H2372-2381 2000年12月

Differential role of K(ATP) channels in late preconditioning against myocardial stunning and infarction in rabbits.
Takano H, Tang XL, Bolli R.
日本医科大学 279(5) H2350-2359 2000年12月

Biphasic response of cardiac NO synthase isoforms to ischemic preconditioning in conscious rabbits.
Xuan YT, Tang XL, Qiu Y, Banerjee S, Takano H, Han H, Bolli R
American journal of physiology. Heart and circulatory physiology 279(5) H2360-71 2000年11月

Cyclooxygenase-2 mediates the cardioprotective effects of the late phase of ischemic preconditioning in conscious rabbits.
Shinmura K, Tang XL, Wang Y, Xuan YT, Liu SQ, Takano H, Bhatnagar A, Bolli R.
Proc Natl Acad Sci U S A. 97(18) 10197-10202 2000年

Nitric oxide donors attenuate myocardial stunning in conscious rabbits.
Shinmura K, Tang XL, Takano H, Hill M, Bolli R
The American journal of physiology 277(6) H2495-503 1999年12月

Nitroglycerin induces late preconditioning against myocardial stunning via a PKC-dependent pathway.
Banerjee S, Tang XL, Qiu Y, Takano H, Manchikalapudi S, Dawn B, Shirk G, Bolli R
The American journal of physiology 277(6) H2488-94 1999年12月

Bifunctional role of protein tyrosine kinases in late preconditioning against myocardial stunning in conscious rabbits.
Dawn B, Xuan YT, Qiu Y, Takano H, Tang XL, Ping P, Banerjee S, Hill M, Bolli R
Circulation research 85(12) 1154-1163 1999年12月

Demonstration of selective protein kinase C-dependent activation of Src and Lck tyrosine kinases during ischemic preconditioning in conscious rabbits.
Ping P, Zhang J, Zheng YT, Li RC, Dawn B, Tang XL, Takano H, Balafanova Z, Bolli R
Circulation research 85(6) 542-550 1999年9月

Ischemic preconditioning increases iNOS transcript levels in conscious rabbits via a nitric oxide-dependent mechanism.
Jones WK, Flaherty MP, Tang XL, Takano H, Qiu Y, Banerjee S, Smith T, Bolli R.
J Mol Cell Cardiol 31(8) 1469-1481 1999年8月

Increased protein synthesis is necessary for the development of late preconditioning against myocardial stunning.
Rizvi A, Tang XL, Qiu Y, Xuan YT, Takano H, Jadoon AK, Bolli R
The American journal of physiology 277(3 Pt 2) H874-84 1999年9月

Nuclear factor-kappaB plays an essential role in the late phase of ischemic preconditioning in conscious rabbits.
Xuan YT, Tang XL, Banerjee S, Takano H, Li RC, Han H, Qiu Y, Li JJ, Bolli R.
Circ Res 84(9) 1095-1109 1999年5月

Isoform-selective activation of protein kinase C by nitric oxide in the heart of conscious rabbits: a signaling mechanism for both nitric oxide-induced and ischemia-induced preconditioning.
Ping P, Takano H, Zhang J, Tang XL, Qiu Y, Li RC, Banerjee S, Dawn B, Balafonova Z, Bolli R.
Circ Res  84(5) 587-604 1999年3月

The nitric oxide hypothesis of late preconditioning.
Bolli R, Dawn B, Tang XL, Qiu Y, Ping P, Xuan YT, Jones WK, Takano H, Guo Y, Zhang J
Basic research in cardiology 93(5) 325-338 1998年10月

Nitric oxide synthase is the mediator of late preconditioning against myocardial infarction in conscious rabbits.
Takano H, Manchikalapudi S, Tang XL, Qiu Y, Rizvi A, Jadoon AK, Zhang Q, Bolli R
Circulation 98(5) 441-449 1998年8月

Nitric oxide donors induce late preconditioning against myocardial stunning and infarction in conscious rabbits via an antioxidant-sensitive mechanism.
Takano H, Tang XL, Qiu Y, Guo Y, French BA, Bolli R.
Circ Res 83(1) 73-84 1998年7月

Direct evidence that protein kinase C plays an essential role in the development of late preconditioning against myocardial stunning in conscious rabbits and that epsilon is the isoform involved.
Qiu Y, Ping P, Tang XL, Manchikalapudi S, Rizvi A, Zhang J, Takano H, Wu WJ, Teschner S, Bolli R.
J Clin Invest 101(10) 2182-2198 1998年5月

Nitric oxide triggers late preconditioning against myocardial infarction in conscious rabbits.
Qiu Y, Rizvi A, Tang XL, Manchikalapudi S, Takano H, Jadoon AK, Wu WJ, Bolli R
The American journal of physiology 273(6 Pt 2) H2931-6 1997年12月

The protective effect of late preconditioning against myocardial stunning in conscious rabbits is mediated by nitric oxide synthase. Evidence that nitric oxide acts both as a trigger and as a mediator of the late phase of ischemic preconditioning.
Bolli R, Manchikalapudi S, Tang XL, Takano H, Qiu Y, Guo Y, Zhang Q, Jadoon AK.
Circ Res  81(6) 1094-1107 1997年12月

高用量Aprindine静注による発作性心房細動停止効果.
新博次, 遠藤康実, 野村敦宣, 小林義典, 斎藤寛和, 井野威, 早川弘一, 小野寺威夫, 高野仁司, 洪基哲, 大村和子.
Therapeutic Research 17 399-403 1996年

Extensive calcification in infarcted myocardium: diagnostic value of ultrafast computed tomography. Cardiology.
Takano H, Endo T, Saito T, Hayakawa H.
Cardiology 81 258-261 1992年
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